Chang Lab Home Research Transition Metal Signaling Activity-Based Sensing Artificial Photosynthesis Publications People Current Members Alumni Photos Group Meetings Contact UC Berkeley DEPT OF CHEMISTRY LBNL MCB HWNI Research Interests Transition Metal Signaling View details » Activity-Based Sensing View details » Artificial Photosynthesis View details » Click here for a virtual lab tour » News Mon Nov 29, 2021 We welcome chembio student Soren to our lab. Happy rotation! Fri Nov 12, 2021 Check out Eva's recently published Nature Reviews on copper and cancer. Congrats! Mon Oct 18, 2021 We're excited to welcome inorganic graduate students Aila and Luke! Wed Sept 15, 2021 We welcome rotation student Jayde to the lab! Wed July 28, 2021 Congrats to Shang for his paper on his microtubule-localizing H2O2 probe! Sat May 15, 2021 Congratulations to our undergraduate seniors Alan, Kaede, and Rachel on your graduation! Looking forward to seeing the great things you do. Mon May 10, 2021 Welcome to first-year ChemBio grad student Abby to the lab! We're excited to have you with us. Tues Feb 23, 2021 Congratulations to Hide and Marco on their new PNAS paper on imaging transcellular peroxide signaling. Tues Dec 15, 2020 Zeming's paper on his potassium sensor RPS-1 has been published in Chemical Science. Fri Nov 20, 2020 Check out Jeff's recently published paper on metal–ligand cooperativity for electrocatalysis! Mon Nov 9, 2020 We welcome first-year grad student Logan to our lab! Mon Sept 29, 2020 Check out Joel and Steven's paper that was recently published in PNAS, featuring a mechanistic study comparing two RNA demethylation pathways. Thurs Sept 10, 2020 Congrats to our former PhD student Eva on accepting a faculty position at UBC! Check out Eva's lab website. Tues Sept 8, 2020 Congrats to our former postdoc Clive on starting a faculty position at University of Hong Kong! Check out Clive's staff page. Tues Sept 1, 2020 Check out our new CO activity-based sensing paper that was published in JACS. Fri Aug 28, 2020 Congrats to Kevin for finishing his PhD, and best of luck in your postdoc with the Bertozzi group at Stanford! Congrats to Peter for finishing his PhD, and best of luck in your postdoc with the Mirkin group at Northwestern! Thurs Aug 20, 2020 Sumin and Clive's paper on activity-based sensing using a copper-directed acyl imidazole strategy appeared in JACS. This work was done in collaboration with the Miller, Saijo, and Hamachi labs. Wed May 6, 2020 Congratulations to Jun on accepting a faculty position at North Carolina State. Check out Jun's new group website. Congratulations to Diana on accepting a faculty position at Virginia Tech! Take a look at Diana's intro video for Virginia Tech, and check out Diana's faculty page. Tues May 5, 2020 We're excited to welcome Angel to our lab! Congrats on completing your lab rotations and officially joining us! Thur Mar 12, 2020 For prospective students with canceled visit weekends, please feel free to reach out to anyone in the lab if you would like more information. Emails are listed under the Current Members section. Check out our new virtual lab tour to see the lab! Tues Jan 7, 2020 Peter's paper appeared in Angew. Chemie. The work was done in collaboration with the Kim lab. Tues Jan 7, 2020 Jun and Lakshmi's paper appeared in ACS Central Science. The work was done in collaboration with the Miller and Toste labs. Thur Sept 5, 2019 Jun and Kevin's review appeared in Acc. Chem. Res. Thur Sept 5, 2019 Congratulations to Shang for finishing his PhD, and best of luck in your postdoc with the Sletten Group at UCLA! Thur Aug 29, 2019 Clive and Sumin's paper appeared in PNAS. The work was done in collaboration with the Brady lab. Mon Aug 5, 2019 Alec and Shang's paper appeared in JACS. The work was a collaboration with the Sigman and Toste labs. Tue July 2 2019 Congratulations to Tim on accepting a faculty position at UC Riverside! Check out his lab website. Mon June 17 2019 Tim and Kevin's review appeared in Curr. Opin. Biotechnology Fri June 7 2019 Diana and Shang's review appeared in Inorg. Chem. Thur June 6 2019 Sumin's paper appeared in Chem. Sci. The work was done in collaboration with the Long lab. Wed June 5 2019 Congratulations to Ming on accepting a faculty position at Fudan University! Thur May 16 2019 Tim and Marie's paper appeared in Cancers.The work was done in collaboration with the Toietta lab. Wed April 24 2019 Shang's paper appeared in JACS. Tues February 12 2019 The lab welcomes visitng scholar Tri and two chemical biology rotation students: Eli and Sarah! Tues February 12 2019 Congratulations to Byungsun on accepting a faculty position at the Korean Institute of Science and Technology! Thurs November 15 2018 The lab welcomes new graduate student Paty and three chemical biology rotation students: Naiya, Paul, and Rei Chi! Tue October 23 2018 Tim's paper was highlighted in JACS Spotlights. Tue October 16 2018 Tim's paper appeared in JACS. The work was done in collaboration with the Stahl lab. Tue October 16 2018 Marie's collaboration with the Skaar lab appeared in Infection and Immunity. Tue August 14 2018 Congratulations to Zhi on accepting a faculty position at the Institute of Coal Chemistry, Chinese Academy of Sciences! Tue August 14 2018 Congratulations to Zeming for finishing his PhD, and best of luck in your postdoc with the Cohen Group at LBNL! Tue August 14 2018 Congratulations to Sumin for finishing her PhD, and best of luck in your postdoc with the Bogyo Group at Stanford! Fri July 27 2018 Tong's paper was featured in a HWNI article. Mon July 9 2018 Peter's paper appeared in Angew. Chem. Int. Ed. The work was done in collaboration with the Kim lab. Tues July 3 2018 Eva's paper appeared in Organometallics. Wed June 27 2018 Congratulations to Allegra for finishing her PhD, and best of luck in your postdoc with the Dorrestein Group at UCSD! Thurs June 14 2018 Lakshmi's viewpoint appeared in Biochemistry. Tues June 12 2018 Tong's paper was featured in a C&E News article. Wed June 6 2018 Tong's paper appeared in Nat. Chem. Biol. The work was done in collaboration with the Isacoff lab. Thur May 3 2018 Clive's paper appeared in J. Am. Chem. Soc. The work was done in collaboration with the Saijo lab. Mon April 16 2018 Kevin and Tim's paper appeared in Angew. Chemie. Int. Ed. The work was done in collaboration with the Shabat lab. Thurs Mar 8 2018 Cheri's paper appeared in Metallomics The work was done in collaboration with the Weber and Pett-Ridge labs. Wed Mar 5 2018 Zhi and Jeff's paper appeared in Angew. Chemie. Int. Ed. The work was done in collaboration with the Coperet and Wen labs. Wed Feb 21 2018 Eva and Jeff's paper appeared in Chem. Sci. Wed Jan 17 2018 Allegra and Audrey's review appeared in Curr. Opin. Chem. Biol Tue Jan 2 2018 Allegra's collaboration appeared in eLIFE. The work was done in collaboration with the Renslo, Monje, and Wang labs. Fri Dec 1 2017 Congratulations to Eva for finishing her PhD, and best of luck in your postdoc with the Mayer Group at Yale! Fri Dec 1 2017 Congratulations to Shixian on accepting a faculty position at Zhejiang University! Tue Nov 14 2017 Allegra and Marie's paper appeared in PNAS. The work was done in collaboration with the Skaar lab at Vanderbilt University and the Stahl lab at UC Berkeley. Wed Oct 13 2017 Congratulations to Cheri for finishing her PhD, and best of luck in your postdoc at the Broad Institute in the Blainey Lab! Thurs Sep 13 2017 Ming, Zhi, and Wei's paper appeared in ACS Central Science. Thurs Aug 17 2017 Thom's collaboration with the KJ Patel Lab appeared in Nature. Mon Aug 14 2017 The lab welcomes three new postdoctoral researchers: Byungsun, Diana, and Joel! Wed Jul 19 2017 The website has been updated to be mobile friendly. Tues Jun 28 2017 Congratulations to Marie for accepting a faculty position at UC Davis! Tues Jun 27 2017 Congratulations to Wei for accepting a faculty position at Miami University of Ohio! Fri Jun 2 2017 The lab welcomes Wendy, a visiting Amgen scholar for the summer from Cornell! Mon May 29 2017 Kevin and Thom's review appeared in Current Opinion in Chemical Biology. Mon May 29 2017 Congratulations to Thom for finishing his PhD, and best of luck in your postdoc at Princeton in the Macmillan Lab! Thu April 13 2017 Congratulations to Chris, who has been elected into the American Academy of Arts and Sciences. Fri April 7 2017 Thom's paper appeared in Chemical Science. The work was done in collaboration with the K. J. Patel lab at the University of Cambridge. Tues April 4 2017 Kevin, Ryan, and Thom's paper appeared in the Journal of the American Chemical Society. The work was done in collaboration with the K. J. Patel lab at the University of Cambridge. Wed Mar 22 2017 Shixian and Shang's paper was highlighted in the April issue of Nature Chemical Biology. Wed Mar 22 2017 Chris' commentary appeared in Accounts of Chemical Research. Mon Mar 20 2017 Shixian and Shang's paper was highlighted in a ACS Chemical Biology spotlight. Mon Feb 27 2017 Shixian and Shang's paper was featured in a In the Pipeline story. Fri Feb 10 2017 Shixian and Shang's paper appeared in Science. The work was done in collaboration with the Toste lab at UC Berkeley. It was featured in a Chemical & Engineering News story, a Berkeley Lab article, and a Phys. Org story. Fri Jan 13 2017 Marie and Ho Yu's paper was featured in a Chemical & Engineering News story. Fri Dec 16 2016 Cheri and Sumin's review appeared in Analytical Chemistry. Fri Dec 2 2016 Marie and Ho Yu's paper appeared in Proceedings of the National Academy of Sciences of the United States of America. The work was done in collaboration with the A. Stahl lab at UC Berkeley. Tues Nov 15 2016 Lakshmi and Joey's paper was featured in a NIGMS Biomedical Beat story. Fri Oct 21 2016 Allegra's paper "An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells" appeared in the Journal of the American Chemical Society. Tues Aug 9 2016 Lakshmi and Joey's paper was featured in a UC Science Today segment and a a PictureFit YouTube video. Mon Aug 8 2016 Today, we're rolling out the new version of the Chang Lab website! Take a look around! Tues July 26 2016 Karla and Safa's review "Thioether Coordination Chemistry for Molecular Imaging of Copper in Biological Systems" appeared in the Israel Journal of Chemistry. Wed July 13 2016 Our collaborative paper "A reactivity-based probe of the intracellular labile ferrous iron pool" appeared in Nature Chemical Biology. Mon June 27 2016 Lakshmi and Joey's paper was featured in a PictureFit YouTube video. Mon June 20 2016 Zhi's collaborative paper "A Molecular Surface Functionalization Approach to Tuning Nanoparticle Electrocatalysts for Carbon Dioxide Reduction" appeared in the Journal of the American Chemical Society. The paper was a result of a collaboration with the Yang and Reimer groups. Mon June 13 2016 Sumin's collaborative paper "Copper Capture in a Thioether-Functionalized Porous Polymer Applied to the Detection of Wilson's Disease" appeared in the Journal of the American Chemical Society. The paper was a result of a collaboration with the Long and Reimer groups. Tues June 7 2016 Lakshmi and Joey's paper "Copper regulates cyclic-AMP-dependent lipolysis" appeared in Nature Chemical Biology. The paper was featured in an LBNL News Story, a UC Berkeley News Story, a Daily Mail News Story, a Genetic Engineering and Biotechnology News Story, a Dr Oz Reviews Story, a Men's Fitness Story, a Deccan Herald News Story, a Fitness First Mag Story, an Indo Asian News Service Story, a Health Canal News Story, a First Post News Story, a Business Standard News Story, a Health Site News Story, a Hindustan Times News Story, a Can-India News Story, a Natural Science News Story, a Times of India News Story, a Money Control News Story, an American Council on Science and Health News Story, a China Topix News Story, a MSN News Story, a Press Liberal News Story, a Headlines News Story, a Sentinel News Story, a Brief Report News Story, an Engine News Story, a 3 Novices News Story, an HT Syndication News Story, and a New York Indian News Story. Mon May 30 2016 Wei's collaborative paper "A reactivity-based [18F]FDG probe for in vivo formaldehyde imaging using positron emission tomography" appeared in Chemical Science. The paper was a result of a collaboration with the D. Wilson laboratory at UCSF. Fri 13 May 2016 Congratulations to Joey on accepting a faculty position at Pennsylvania State University! Check out his new faculty website! Fri 13 May 2016 Congratulations to Ryan on accepting a faculty position at Ursinus College! Tues 23 Feb 2016 Check out Song's new faculty website! Sat 13 Feb 2016 Congratulations to Jean-Marc on accepting a position as an Assistant Adjunct Professor at the Institute for Neurodegenerative Diseases, UCSF! Mon 25 Jan 2016 Congratulations to Song on accepting a faculty position at Cornell University! Mon Nov 2 2015 Song's collaborative paper "Metal–Organic Frameworks for Electrocatalytic Reduction of Carbon Dioxide" appeared in the Journal of the American Chemical Society. The paper was a result of a collaboration with the O. Yaghi and P. Yang labs. Fri Oct 2 2015 Chris' commentary "Searching for Harmony in Transition-Metal Signaling" appeared in Nature Chemical Biology. Fri Oct 2 2015 Allegra's review "Recognition- and Reactivity-Based Fluorescent Probes for Studying Transition Metal Signaling in Living Systems" appeared in Accounts of Chemical Research. Fri Sept 11 2015 Eva's collaborative paper "Hybrid bioinorganic approach to solar-to-chemical conversion" was featured in an IFL Science! Story. The paper was a result of a collaboration with the M. Chang and P. Yang labs. Fri 11 Sept 2015 Congratulations to Annie Chantarojsiri for finishing her PhD, and best of luck in your postdoc at UC Irvine! Mon 7 Sept 2015 Thom's paper "An Aza-Cope Reactivity-Based Fluorescent Probe for Imaging Formaldehyde in Living Cells" appeared in the Journal of the American Chemical Society. The paper was profiled in a Chemical & Engineering News Story. Sun 30 Aug 2015 Song's collaborative paper "Covalent organic frameworks comprising cobalt porphyrins for catalytic CO2 reduction in water" appeared in Science. The paper is a result of a collaboration with the P. Yang and O. Yaghi labs, and was profiled in an LBNL News Story as well as a Science News Story. Wed 26 Aug 2015 Eva's collaborative paper "Hybrid bioinorganic approach to solar-to-chemical conversion" appeared in Proceedings of the National Academy of Sciences of the United States of America. The paper is a result of a collaboration with the M. Chang and P. Yang labs, and was profiled in an LBNL News Story, a ScienceDaily News Story, a Demanjo News Story, a Science Newsline News Story, a Tech News Coverage News Story, an Adaptive Scientist News Story, and a Guldar News Story. It was also featured in the DOE's Science Headlines. Fri 7 July 2015 Annie's collaborative review "Metal-Polypyridyl Catalysts for Electro- and Photochemical Reduction of Water to Hydrogen" appeared in Accounts of Chemical Research. The review was written in collaboration with the J. Long lab. Mon 22 June 2015 Jonah and Eva's collaborative paper, "Bioinspired design of redox-active ligands for multielectron catalysis: effects of positioning pyrazine reservoirs on cobalt for electro- and photocatalytic generation of hydrogen from water," appeared in Chemical Science. The paper is a result of a collaboration with the M. Head-Gordon, J. Long, and F. Castellano labs. Sun 7 June 2015 Annie's paper "Water-Soluble Iron(IV)-Oxo Complexes Supported by Pentapyridine Ligands: Axial Ligand Effects on Hydrogen Atom and Oxygen Atom Transfer Reactivity" appeared in Inorganic Chemistry. Fri 5 June 2015 Thom and Carl's review "Chemical Approaches to Discovery and Study of Sources and Targets of Hydrogen Peroxide Redox Signaling Through NADPH Oxidase Proteins" appeared in the Annual Review of Biochemistry. The review was written in collaboration with the K. Carroll lab. Tues 21 April 2015 Eva's collaborative paper was profiled in a Statesman article. The paper is a result of a collaboration with the P. Yang and M. Chang labs. Mon 20 April 2015 Eva's collaborative paper was profiled in a Huffington Post article. The paper is a result of a collaboration with the P. Yang and M. Chang labs. Fri 17 April 2015 Eva's collaborative paper, "Nanowire-Bacteria Hybrids for Unassisted Solar Carbon Dioxide Fixation to Value-Added Chemicals," appeared in Nano Lett. and was profiled in an LBNL News Story, a Tech Times News Story, a Science Times News Story, and a News Everyday News Story. It was also featured in the DOE's Science Headlines. The paper is a result of a collaboration with the P. Yang and M. Chang labs. Wed 4 March 2015 Congratulations to Chang lab alumnus Sara Thoi on accepting a faculty position at Johns Hopkins University! Tues 24 Feb 2015 Joey, Allegra, and Karla's review, "Synthetic fluorescent probes for studying copper in biological systems," appeared in Chemical Society Reviews. Tues 24 Feb 2015 Vivian's review, "Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems," appeared in Chemical Society Reviews. Sun 30 Nov 2014 Sheel and Jeff's PNAS paper was profiled in an LBNL News Story, a C&E News Story, and a R&D Magazine News Story. Fri 7 Nov 2014 Sheel and Jeff's paper, "Copper is an endogenous modulator of neural circuit spontaneous activity," appeared in PNAS. Fri 17 Oct 2014 Brian's paper, "A Boronate-Caged [18F]FLT Probe for Hydrogen Peroxide Detection Using Positron Emission Tomography," appeared in JACS. Mon 19 Aug 2014 The Chang Lab welcomes the new first-year students to the department! Come visit us at the Chembio poster session today (noon-2pm, B1 Stanley) or in our labs (401, 535, 610 Latimer). Open house is Monday, 8/25 from 1-4 PM in 532 Latimer. Mon 19 Aug 2014 Publication of Amanda's latest paper, "A Well-Defined Terminal Vanadium(III) Oxo Complex," in Inorganic Chemistry marks the lab's 100th publication (125 overall)! The paper is a result of a collaboration with the Long and Neese labs. Mon 19 Aug 2014 Our metals in neurobiology work presented at ACS was highlighted in an LBNL story, which was reposted by R&D magazine. Mon 4 Aug 2014 Congratulations to Carl Onak and Vivian Lin for finishing their PhDs! Thurs 29 May 2014 Congratulations to Brian on accepting a faculty position at the University of Denver! Wed 14 May 2014 The lab welcomes Corey into the Chang lab family! Mon 21 April 2014 Congratulations to Chang lab alumnus Bryan Dickinson on accepting a faculty position at the University of Chicago! Tue 8 Apr 2014 Congratulations to Jeff on accepting a faculty position at the University of Illinois at Urbana-Champaign! Tue 8 Apr 2014 Congratulations to Jonah on accepting a faculty position at the University of Mississippi! Tue 8 Apr 2014 Congratulations to Michael on accepting a faculty position at the Texas A&M! Wed 12 Feb 2014 Take a look at the redesigned research section of the website and learn about our four research areas: Chemical Biology, Bioinorganic Chemistry, Organic Chemistry, and Inorganic Chemistry! Tue 19 Nov 2013 Yujie's paper, "Electrodeposited Cobalt-Sulfide Catalyst for Electrochemical and Photoelectrochemical Hydrogen Generation from Water," appeared in JACS. Mon 11 Nov 2013 Congratulations to Harini on starting your new job at Genentech! Tue 24 Sep 2013 Ho Yu, Jeff, and Annie's paper, "Molecular Imaging of Labile Iron(II) Pools in Living Cells with a Turn-On Fluorescent Probe," appeared in JACS. Mon 16 Sep 2013 Sara's paper, "Visible-Light Photoredox Catalysis: Selective Reduction of Carbon Dioxide to Carbon Monoxide by a Nickel N-Heterocyclic Carbene-Isoquinoline Complex," appeared in JACS. Mon 16 Sep 2013 Congratulations to Ho Yu on starting your faculty position at the University of Hong Kong! Mon 16 Sep 2013 Congratulations to Yujie on starting your faculty position at Utah State University! Mon 16 Sep 2013 Congratulations to Sheel for finishing your PhD and on starting your postdoc in the Arnold Group at Caltech! Mon 16 Sep 2013 Congratulations to Sara for finishing your PhD and on starting your postdoc in the Haile Group at Caltech! Tue 13 Aug 2013 The group's latest paper, "Catalytic Proton Reduction with Transition Metal Complexes of the Redox-active Ligand bpy2PYMe," appeared in Chemical Science. Wed 3 Jul 2013 Vivian and Alex's paper on cell-trappable hydrogen sulfide probes was highlighted in a Faculty of 1000 Recommendation. Tue 25 Jun 2013 Vivian and Bryan's chapter, "Boronate-Based Fluorescent Probes: Imaging Hydrogen Peroxide in Living Systems," appeared in the latest volume of Methods in Enzymology. Mon 17 Jun 2013 Vivian and Alex's paper on cell-trappable hydrogen sulfide probes was highlighted in a Chemical Research in Toxicology Spotlight. Fri 7 Jun 2013 Bryan and Vivian's paper, "Preparation and use of MitoPY1 for imaging hydrogen peroxide in mitochondria of live cells," appeared in Nature Protocols. Tue 28 May 2013 The lab's work on copper imaging was profiled in an LBNL News Highlight. Tue 23 Apr 2013 Vivian and Alex's paper was highlighted in C&E News. Thu 18 Apr 2013 Vivian and Alex's paper, "Cell-trappable Fluorescent Probes for Endogenous Hydrogen Sulfide Signaling and Imaging H2O2-Dependent H2S Production," appeared in PNAS. Fri 22 Feb 2013 Amanda, Nick, and Julian's paper, "A Mechanistic Study of Proton Reduction Catalyzed by a Pentapyridine Cobalt Complex: Evidence for Involvement of an Anation-Based Pathway," appeared in Chemical Science. Sun 27 Jan 2013 Genevieve's paper, "Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation," appeared in JACS. Mon 21 Jan 2013 Congratulations to Mike on graduating, and best of luck at Gmab! Mon 21 Jan 2013 Best of luck to Amanda at Los Alamos National Lab! Mon 21 Jan 2013 Congratulations to Genevieve on graduating, and best of luck in your postdoc at Harvard/MGH! Thu 13 Dec 2012 Jeff and Sheel's review, "Reaction-based small-molecule fluorescent probes for chemoselective bioimaging," appeared in Nature Chemistry. Mon 22 Oct 2012 Sara and Yujie's review, "Complexes of earth-abundant metals for catalytic electrochemical hydrogen generation under aqueous conditions," appeared in Chemical Society Reviews. Mon 22 Oct 2012 Vivian's review on fluorescent probes for H2S appeared in Current Opinion in Chemical Biology. Mon 24 Sep 2012 Yujie's paper, "Photocatalytic generation of hydrogen from water using a cobalt pentapyridine complex in combination with molecular and semiconductor nanowire photosensitizers," appeared in Chemical Science. Mon 24 Sep 2012 Brian and Alex's paper on a reaction-based fluorescent probe for carbon monoxide was highlighted in C&E News. Sun 16 Sep 2012 Brian and Alex's paper on a reaction-based fluorescent probe for carbon monoxide appeared in JACS. Sun 26 Aug 2012 Congratulations to Chang lab alumnus Bryan Dickinson for winning the Nobel Laureate Signature Award from the ACS for best thesis! Sun 26 Aug 2012 Hill, Mike, and Nick's paper on vanadium organoazide complexes and their conversion to terminal vanadium imides appeared in Inorganic Chemistry. Tue 31 Jul 2012 Congratulations to Julian on earning your PhD! Best of luck at Kinestral Technologies. Tue 31 Jul 2012 Congratulations to Alex on starting your lab at SMU Chemistry! Best of luck in your independent career. Tue 24 Apr 2012 Ho Yu and Liz's paper, "A selective reaction-based fluorescent probe for detecting cobalt in living cells," appeared in ChemComm. Mon 23 Apr 2012 Sara and Hema's paper, "Electrochemical generation of hydrogen from acetic acid using a molecular molybdenum-oxo catalyst," appeared in Energy and Environmental Science. Wed 18 Apr 2012 Emily and Liz's paper, "A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model," appeared in Chemical Science today. Thu 8 Mar 2012 Sara and Hema's paper, "Computational and Experimental Study of the Mechanism of Hydrogen Generation from Water by a Molecular Molybdenum-Oxo Electrocatalyst," appeared in JACS today. Fri 10 Feb 2012 Hema and Yujie's paper, "A Molecular MoS2 Edge Site Mimic for Catalytic Hydrogen Generation," appeared in Science and was highlighted in a UC Berkeley press release, an LBNL press release, a Daily Cal article, and a C&E News article. Wed 1 Feb 2012 Genevieve and Tasuku's paper on a fluorescent near-IR probe for imaging copper in living mice appeared today in PNAS. Wed 4 Jan 2012 Julian and Hill's paper, "A High-Spin Iron(IV)-Oxo Complex Supported by a Trigonal Nonheme Pyrrolide Platform," appeared today in JACS. Fri 28 Oct 2011 Alex and Liz's paper on fluorescent reaction-based H2S probes was featured in C&E News. Tue 6 Sep 2011 Bryan's paper on a nuclear H2O2 probe and its use in monitoring sirtuin-mediated oxidative stress appeared in Chemistry & Biology. Thu 11 Aug 2011 Alex and Genevieve's review appeared today in Accounts of Chemical Research. Wed 3 Aug 2011 May's paper on a ratiometric two-photon hydrogen peroxide probe appeared in ChemComm. Tue 19 Jul 2011 Bryan's review on the chemistry and biology of reactive oxygen species in cellular signaling and stress responses appeared today in Nature Chemical Biology. Mon 11 Jul 2011 Liz is the recipient of the 2011 Dalton Young Researchers Award. Congratulations! Mon 20 Jun 2011 Alex and Liz's paper on a selective H2S probe appeared in JACS. Wed 25 May 2011 Yujie, Julian, and Nick's paper on molecular cobalt pentapyridine catalysts for generating hydrogen from water appeared today in JACS. Mon 16 May 2011 Sheel's paper on a new mitochondrial copper probe and its application to imaging mitochondrial copper pools in fibroblasts with mutant SCO1 and SCO2 enzymes appeared today in JACS. Tue 10 May 2011 Sara's paper on nickel N-heterocyclic carbene-pyridine complexes that exhibit selectivity for electrocatalytic reduction of carbon dioxide over water appeared today in ChemComm. Tue 29 Mar 2011 Sheel, Dylan, Christine, and Evan's paper on copper redistributions in neuronal cells appeared yesterday in PNAS. Mon 21 Mar 2011 May and Aaron's paper on a dendrimer-based fluorescent sensor for imaging H2O2 and pH gradients in cells appeared last week in Chemical Science. Wed 9 Mar 2011 Added today: a new group photo and pictures of Dylan's going away party at Albany Bowl. Sat 5 Mar 2011 Alex's paper on a hyperpolarized 13C MRI probe for hydrogen peroxide appeared this week in JACS. Thu 10 Feb 2011 Genevieve's recent PNAS paper on hydrogen peroxide imaging in mice was featured on the Lawrence Berkeley Lab website. Wed 2 Feb 2011 Nick, Mike, and Hill's paper on a vanadium complex that binds nitrous oxide appeared today in JACS. Tue 11 Jan 2011 Bryan's paper on H2O2 imaging in neural stem cells and Genevieve's paper on H2O2 imaging in live mice were highlighted in C&E News. Fri 31 Dec 2010 Added today: photos from Anne's going away party at Jupiter. Sun 26 Dec 2010 Bryan's paper on redox signaling in neural stem cells appeared today in Nature Chemical Biology. Wed 22 Dec 2010 Genevieve's recent PNAS paper on hydrogen peroxide imaging in mice was given a "must read" rating by the Faculty of 1000. Wed 8 Dec 2010 Hill's paper on slow magnetic relaxation in trigonal pyramidal iron(II) pyrrolide complexes appeared today in JACS. Mon 29 Nov 2010 Genevieve's paper on hydrogen peroxide imaging in mice appeared today in PNAS. Mon 22 Nov 2010 Evan, Carl, and Liz's paper describing a photocaged hydrogen peroxide generator appeared last week in JACS. Fri 5 Nov 2010 Added today: photos of Bryan's going away party at the Trappist. Mon 1 Nov 2010 Congratulations to Bryan on earning your Ph.D. Best of luck at Harvard! Thu 21 Oct 2010 Evan and Bryan's recent PNAS paper on the role of aquaporins in cellular uptake of hydrogen peroxide was highlighted in ACS Chemical Biology and was given a "must read" rating by the Faculty of 1000. Tue 31 Aug 2010 Congratulations to Hill on earning your Ph.D. and Danielle on earning your M.S. Best of luck to both of you at Caltech! Tue 31 Aug 2010 Fall group meetings start Sep 1. First-years, join us for pizza on Wednesdays at 7:00pm in 775B Tan. Tue 24 Aug 2010 Added today: Techniques that we use in our research. Thu 19 Aug 2010 Added today: Bryan's photo album. Thu 19 Aug 2010 Added today: Photos of group dinner and Pink Saturday and Hawaii retreat, 2009. Wed 18 Aug 2010 Added today: Photos of the group trip to the Giants game on HHMI Staff Appreciation Day. Tue 17 Aug 2010 First-year students: join us for our group meeting tonight in 775B Tan at 7:00pm. Tue 17 Aug 2010 The Chang Lab welcomes the new first-year students to the department! Come visit us at the Chembio poster session today (noon-2pm, 775 Tan) or in our labs (401, 535, 610 Latimer).