Orbital exenteration: A 15-year study of 38 cases
— Macquarie University Skip to main navigation Skip to search Skip to main content Help & FAQ Home Profiles Research Units Projects Research Outputs Prizes Activities Press / Media Impacts Search by expertise, name or affiliation Orbital exenteration A 15-year study of 38 cases Arie Y. Nemet*, Peter Martin, Ross Benger, Georgina Kourt, Vidushi Sharma, Raf Ghabrial, Jenny Danks *Corresponding author for this work Faculty of Medicine, Health and Human Sciences Research output: Contribution to journal › Article 38 Citations (Scopus) Overview Fingerprint Abstract PURPOSE: To determine the clinical indications and outcomes after orbital exenteration when histologic margins were reported as "clear," examining factors affecting local and systemic recurrences and mortality. METHODS: Retrospective case review of exenterations performed in Sydney Eye Hospital in Sydney, Australia, between 1990 and 2004. Reviewed data indications for exenteration, histopathologic diagnosis, and recurrences on follow-up. RESULTS: Secondary intraorbital spread of malignant adnexal tumors was the most common indication for exenteration (34 of 38). Among these, the site of the primary neoplasm was the eyelid in 19 cases and the ocular surface in 12 cases. Exenteration was total in 26 cases, subtotal in 8 cases, and extended in 4 cases. In 11 cases, a dermis-fat graft was used for socket reconstruction; 24 cases were allowed to granulate spontaneously. The average healing time was 5 months (range, 4-6 months) for spontaneous granulation, and 6 weeks (range, 4-8 weeks) for dermis-fat grafts. Perineural spread was demonstrated histopathologically in 7 specimens. During follow-up (median, 48 months), there were 9 recurrences (23.7%): 3 local and 6 systemic. Seven patients (18.4%) died of the disease during the follow-up period. CONCLUSIONS: Dermis-fat grafts for reconstruction of the exenterated socket seem to optimize the aesthetic results. The first year is the most important period for follow-up of local recurrences, but systemic examination is needed for the longer follow-up. This may have implications in terms of reconstruction and adjunctive treatment following exenteration surgery. Original language English Pages (from-to) 468-472 Number of pages 5 Journal Ophthalmic plastic and reconstructive surgery Volume 23 Issue number 6 DOIs https://doi.org/10.1097/IOP.0b013e318158e994 Publication status Published - Nov 2007 Access to Document 10.1097/IOP.0b013e318158e994 Link to publication in Scopus Fingerprint Dive into the research topics of 'Orbital exenteration: A 15-year study of 38 cases'. Together they form a unique fingerprint. Dermis Medicine & Life Sciences Recurrence Medicine & Life Sciences Fats Medicine & Life Sciences Transplants Medicine & Life Sciences Eyelid Neoplasms Medicine & Life Sciences Neoplasms by Site Medicine & Life Sciences Esthetics Medicine & Life Sciences Mortality Medicine & Life Sciences View full fingerprint Cite this APA Author BIBTEX Harvard Standard RIS Vancouver Nemet, A. Y., Martin, P., Benger, R., Kourt, G., Sharma, V., Ghabrial, R., & Danks, J. (2007). Orbital exenteration: A 15-year study of 38 cases. Ophthalmic plastic and reconstructive surgery, 23(6), 468-472. https://doi.org/10.1097/IOP.0b013e318158e994 Nemet, Arie Y. ; Martin, Peter ; Benger, Ross ; Kourt, Georgina ; Sharma, Vidushi ; Ghabrial, Raf ; Danks, Jenny. / Orbital exenteration : A 15-year study of 38 cases. In: Ophthalmic plastic and reconstructive surgery. 2007 ; Vol. 23, No. 6. pp. 468-472. @article{0d09e40ccbfb4a448ee5f0295338f1d3, title = "Orbital exenteration: A 15-year study of 38 cases", abstract = "PURPOSE: To determine the clinical indications and outcomes after orbital exenteration when histologic margins were reported as {"}clear,{"} examining factors affecting local and systemic recurrences and mortality. METHODS: Retrospective case review of exenterations performed in Sydney Eye Hospital in Sydney, Australia, between 1990 and 2004. Reviewed data indications for exenteration, histopathologic diagnosis, and recurrences on follow-up. RESULTS: Secondary intraorbital spread of malignant adnexal tumors was the most common indication for exenteration (34 of 38). Among these, the site of the primary neoplasm was the eyelid in 19 cases and the ocular surface in 12 cases. Exenteration was total in 26 cases, subtotal in 8 cases, and extended in 4 cases. In 11 cases, a dermis-fat graft was used for socket reconstruction; 24 cases were allowed to granulate spontaneously. The average healing time was 5 months (range, 4-6 months) for spontaneous granulation, and 6 weeks (range, 4-8 weeks) for dermis-fat grafts. Perineural spread was demonstrated histopathologically in 7 specimens. During follow-up (median, 48 months), there were 9 recurrences (23.7{\%}): 3 local and 6 systemic. Seven patients (18.4{\%}) died of the disease during the follow-up period. CONCLUSIONS: Dermis-fat grafts for reconstruction of the exenterated socket seem to optimize the aesthetic results. The first year is the most important period for follow-up of local recurrences, but systemic examination is needed for the longer follow-up. This may have implications in terms of reconstruction and adjunctive treatment following exenteration surgery.", author = "Nemet, {Arie Y.} and Peter Martin and Ross Benger and Georgina Kourt and Vidushi Sharma and Raf Ghabrial and Jenny Danks", year = "2007", month = "11", doi = "10.1097/IOP.0b013e318158e994", language = "English", volume = "23", pages = "468--472", journal = "Ophthalmic plastic and reconstructive surgery", issn = "0740-9303", publisher = "Lippincott Williams and Wilkins", number = "6", } Nemet, AY, Martin, P, Benger, R, Kourt, G, Sharma, V, Ghabrial, R & Danks, J 2007, 'Orbital exenteration: A 15-year study of 38 cases', Ophthalmic plastic and reconstructive surgery, vol. 23, no. 6, pp. 468-472. https://doi.org/10.1097/IOP.0b013e318158e994 Orbital exenteration : A 15-year study of 38 cases. / Nemet, Arie Y.; Martin, Peter; Benger, Ross; Kourt, Georgina; Sharma, Vidushi; Ghabrial, Raf; Danks, Jenny. In: Ophthalmic plastic and reconstructive surgery, Vol. 23, No. 6, 11.2007, p. 468-472. Research output: Contribution to journal › Article TY - JOUR T1 - Orbital exenteration T2 - A 15-year study of 38 cases AU - Nemet, Arie Y. AU - Martin, Peter AU - Benger, Ross AU - Kourt, Georgina AU - Sharma, Vidushi AU - Ghabrial, Raf AU - Danks, Jenny PY - 2007/11 Y1 - 2007/11 N2 - PURPOSE: To determine the clinical indications and outcomes after orbital exenteration when histologic margins were reported as "clear," examining factors affecting local and systemic recurrences and mortality. METHODS: Retrospective case review of exenterations performed in Sydney Eye Hospital in Sydney, Australia, between 1990 and 2004. Reviewed data indications for exenteration, histopathologic diagnosis, and recurrences on follow-up. RESULTS: Secondary intraorbital spread of malignant adnexal tumors was the most common indication for exenteration (34 of 38). Among these, the site of the primary neoplasm was the eyelid in 19 cases and the ocular surface in 12 cases. Exenteration was total in 26 cases, subtotal in 8 cases, and extended in 4 cases. In 11 cases, a dermis-fat graft was used for socket reconstruction; 24 cases were allowed to granulate spontaneously. The average healing time was 5 months (range, 4-6 months) for spontaneous granulation, and 6 weeks (range, 4-8 weeks) for dermis-fat grafts. Perineural spread was demonstrated histopathologically in 7 specimens. During follow-up (median, 48 months), there were 9 recurrences (23.7%): 3 local and 6 systemic. Seven patients (18.4%) died of the disease during the follow-up period. CONCLUSIONS: Dermis-fat grafts for reconstruction of the exenterated socket seem to optimize the aesthetic results. The first year is the most important period for follow-up of local recurrences, but systemic examination is needed for the longer follow-up. This may have implications in terms of reconstruction and adjunctive treatment following exenteration surgery. AB - PURPOSE: To determine the clinical indications and outcomes after orbital exenteration when histologic margins were reported as "clear," examining factors affecting local and systemic recurrences and mortality. METHODS: Retrospective case review of exenterations performed in Sydney Eye Hospital in Sydney, Australia, between 1990 and 2004. Reviewed data indications for exenteration, histopathologic diagnosis, and recurrences on follow-up. RESULTS: Secondary intraorbital spread of malignant adnexal tumors was the most common indication for exenteration (34 of 38). Among these, the site of the primary neoplasm was the eyelid in 19 cases and the ocular surface in 12 cases. Exenteration was total in 26 cases, subtotal in 8 cases, and extended in 4 cases. In 11 cases, a dermis-fat graft was used for socket reconstruction; 24 cases were allowed to granulate spontaneously. The average healing time was 5 months (range, 4-6 months) for spontaneous granulation, and 6 weeks (range, 4-8 weeks) for dermis-fat grafts. Perineural spread was demonstrated histopathologically in 7 specimens. During follow-up (median, 48 months), there were 9 recurrences (23.7%): 3 local and 6 systemic. Seven patients (18.4%) died of the disease during the follow-up period. CONCLUSIONS: Dermis-fat grafts for reconstruction of the exenterated socket seem to optimize the aesthetic results. The first year is the most important period for follow-up of local recurrences, but systemic examination is needed for the longer follow-up. This may have implications in terms of reconstruction and adjunctive treatment following exenteration surgery. UR - http://www.scopus.com/inward/record.url?scp=36348967122&partnerID=8YFLogxK U2 - 10.1097/IOP.0b013e318158e994 DO - 10.1097/IOP.0b013e318158e994 M3 - Article VL - 23 SP - 468 EP - 472 JO - Ophthalmic plastic and reconstructive surgery JF - Ophthalmic plastic and reconstructive surgery SN - 0740-9303 IS - 6 ER - Nemet AY, Martin P, Benger R, Kourt G, Sharma V, Ghabrial R et al. Orbital exenteration: A 15-year study of 38 cases. Ophthalmic plastic and reconstructive surgery. 2007 Nov;23(6):468-472. https://doi.org/10.1097/IOP.0b013e318158e994 Powered by Pure, Scopus & Elsevier Fingerprint Engine™ © 2021 Elsevier B.V. We use cookies to help provide and enhance our service and tailor content. By continuing you agree to the use of cookies Log in to Pure About web accessibility
