Parasites and Microbes – Wellcome Sanger Institute Skip to main content Careers | Find us | Contact us About Our Vision Our History Leadership Strategy and Funding Influencing Policy Equality in Science Careers Study Research Policies Campus Connections Admin Groups Branding and Logos Science COVID-19 Research Programmes Scientific Groups Collaborations Tools Data Sanger Projects Publications Research Policies Sanger Seminar Series People Leadership Faculty Associate Faculty Honorary Faculty International Fellows Science Staff Non-science Staff Full A-Z Innovation Innovation at the Institute For Industry For Researchers Case Studies Our Spin-Outs Sanger Technologies News OverviewFaculty positions availableRelated groupsRelated International Fellows and Honorary FacultyAssociated researchRelated news and blogs Emphyrio, Pixabay Programme Parasites and Microbes Overview We are using genomics to get at important problems in infectious disease, with a strong desire to translate this into tools for disease control and elimination, but we are also at the forefront of basic research into microbial ecology, evolutionary genetics and the biology of parasitism. David Goulding E.coli adhering via specialized bundle forming pili to a loose matrix around the collar Trichuris eggs. This helps the E.coli to colonize the region and eventually leads to complete degradation of the polar mucus plug, which is essential for hatching and releasing the parasitic worm inside. Faculty positions available The Parasites and Microbes Programme is seeking to recruit two Faculty leaders at any level with research interests in the two following strategic areas: ◆ using population genomics to characterise malaria biology and improve malaria control ◆ respiratory metagenomics, with a focus on how interactions between viruses, bacteria, fungi and human hosts can combine to cause disease. See more about the positions Faculty positions available The Parasites and Microbes Programme is seeking two exceptional research scientists. You will join our Faculty who have diverse expertise in biology, genetics, medicine, pathology, technology, informatics, computational science, mathematics, and statistics. They work alongside each other with a particular scientific culture and intellectual critical mass supported by technical, IT, and analytic support to develop and follow bold ideas in an agile manner. Our exceptional funding enables Faculty to focus their energy on their science, by providing a comprehensive package of support and salaries. We provide excellent benefits and relocation support, along with rewarding and flexible employment terms to enable you to thrive and develop your scientific career at our Institute. Find out more and apply Related groups Science group Aanensen Group Genomic Epidemiology of Infectious Diseases Our mission is to inform control strategies and interventions on a local, national and international scale. Our group consists of a ... Science group Berriman Group Parasite Genomics The Parasite Genomics group uses comparative and functional genomics approaches to investigate the biology of helminths and protozoan parasites. Science group COVID-19 Genomics Initiative at the Wellcome Sanger Institute Parasites and Microbes We will provide real-time genomic monitoring of SARS-CoV-2 in the UK to aid public health response. We will also monitor for ... Science group Genomics of Pneumonia, Meningitis and Neonatal Sepsis Parasites and Microbes We study variation in the genomes of major bacterial pathogens to understand their evolution in the context of disease and asymptomatic ... Science group Kwiatkowski Group Natural genetic variation The Kwiatkowski group investigates Plasmodium, Anopheles and human genome variation in large clinical and epidemiological studies carried out with partners in ... Science group Lawley Lab Host-microbiota interactions The host-microbiota Interactions laboratory studies the mechanisms that underlie how micro-organisms in the gut, nasopharynx and uro-gential tract interact with their ... Science group Lawniczak Group Evolutionary genetics The Lawniczak lab is using single cell technologies and whole genome sequencing to study transmission biology. We are carrying out research ... Science group Lee Group Malaria Parasite Drug Resistance The group aims to understand how malaria parasites become resistant to antimalarial compounds. They study drugs in clinical use as well ... Science group Parasites and Microbes Administration Parasites and Microbes The activities of the team include anything from organising international travel itineraries, servicing multi-million pound collaborative grants and facilitating Faculty management ... Science group Pathogen Informatics Parasites and Microbes The Pathogen Informatics team develop and maintain software applications and systems to support the research activities of the Parasites and Microbes ... Science group PlasmoGEM Parasites and Microbes PlasmoGEM (the Plasmodium Genetic Modification Project) is an interdisciplinary group at the Wellcome Sanger Institute focussed on changing the scale of ... Science group Thomson Group Bacterial genomics and evolution The bacterial genomics and evolution team focuses primarily on using whole-genome sequencing approaches to study the patterns and drivers for historical ... Science group Wright Group Cell Surface Signalling Laboratory The Cell Surface Signalling Laboratory investigates the molecular basis of cellular recognition processes to identify new therapeutic targets for both genetic ... previous related groups Science group Billker Group Rodent models of malaria At the Sanger Institute Oliver Billker's group used experimental genetics in rodent models to study the basic biology of malaria ... Science group Dougan Group Microbial Pathogenesis The Microbial Pathogenesis team, under the leadership of Professor Gordon Dougan, focused on the genetic analysis of the interactions between ... Science group Parkhill Group Pathogen Genomics The Pathogen genomics team, headed by Julian Parkhill, used high-throughput genomic and phenotypic analysis of bacteria to understand their virulence, ... Science group Rayner Group Human-parasite interactions in malaria The group uses large-scale experimental approaches to identify and prioritise drug and vaccine targets in malaria. Focusing on the blood stages ... Related International Fellows and Honorary Faculty International Fellow Prof Alfred Amambua-Ngwa Alfred is a Cameroonian Biochemist with experience and research interest in the use of biotechnology and genomics to understand the evolution ... International Fellow Dr Claire Chewapreecha Claire is a computational biologist based in Thailand and committed to improving public health in Southeast Asia through the development of ... Honorary Faculty Prof Abdoulaye Djimdé Abdoulaye Djimdé is a leading malaria researcher based in Mali, working primarily on the genetic epidemiology of antimalarial drug resistance in ... International Fellow Dr Gregorio Iraola Gregorio is a computational microbiologist based in Uruguay. He applies high-throughput sequencing, bioinformatics and culturing to investigate the evolutionary patterns of ... Honorary Faculty Dr Samuel Kariuki Sam utilises molecular tools to investigate the field epidemiology of major enteric infections and antimicrobial resistance ecology and transmission in Kenya ... International Fellow Dr Annettee Nakimuli Annettee Nakimuli is a leading maternal health researcher based in Uganda, focused primarily on investigating the aetiology, treatment, prevention and long ... International Fellow Prof Pablo Tsukayama Pablo is a Peruvian microbiologist with a long-standing interest in infectious diseases affecting Latin American populations. His research combines methods in ... Associated research Collaborations Collaboration 50 Helminth Genomes Project (50HGP) We are surveying the genomes of the parasitic worms that have the greatest impact on human, agricultural and veterinary disease ... Collaboration MRC Centre for Genomics and Global Health (CGGH) CCGH mission is to accelerate the translation of large-scale genomic data into meaningful information and effective tools to combat infectious diseases ... Collaboration MalariaGEN (Malaria Genomic Epidemiology Network) MalariaGEN is a data-sharing community working to develop new tools to control malaria by integrating epidemiology with genome science. Collaboration Pathogen Overseas Courses The Pathogen groups work with the Wellcome Trust Advanced Courses to run a number of courses on pathogen genomics and biology ... Collaboration The Centre for Genomic Pathogen Surveillance (CGPS) Our mission is to inform pathogen control strategies and interventions on a local, national and international scale. Tools & software Tool ARNIE - AVEXIS Receptor Network with Integrated Expression ARNIE is an online database that integrates the extracellular protein interaction network generated in our lab using AVEXIS technology with ... Tool Ag1000g The Anopheles Gambiae 1000 Genome project is a global collaboration using whole genome deep sequencing to provide a high-resolution view ... Tool Artemis Comparison Tool (ACT) ACT is a Java application for displaying pairwise comparisons between two or more DNA sequences. Tool Malaria Cell Atlas The Malaria Cell Atlas aims to provide a resource of single cell transcriptomic data across the full lifecycle of the parasite Tool Pf3k The Pf3k project is a global collaboration using the latest sequencing technologies to provide a high-resolution view of the natural ... Data Data set Helminth Data All helminth genomes sequenced by the Sanger Institute Data set Protozoan Data All protozoan genomes sequenced by the Sanger Institute Data set Virus Data All viral genomes sequenced by the Sanger Institute previous data sets Data set Bacterial Data This Archived page provides historical information on the genome sequences of bacteria that were sequenced at the Wellcome Sanger Institute and ... Related news and blogs Show all news 14 Sep 2021 Evidence-based national policies are essential to curb local COVID-19 infections By using genomic surveillance and mobile phone data, researchers have uncovered useful insights into the management of the COVID-19 pandemic in ... 23 Aug 2021 Defining Success Five inspirational speakers share their journeys, definitions of success, and lessons learnt in the space of diversity and inclusion. 10 Aug 2021 Fighting the spread of drug-resistant malaria with genetic surveillance In-depth genomic surveillance of the malaria parasite over multiple countries has tracked regions of drug resistance Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA. 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