Science – Wellcome Sanger Institute Skip to main content Careers | Find us | Contact us About Our Vision Our History Leadership Strategy and Funding Influencing Policy Equality, diversity and inclusion Careers Study Research Policies Campus Connections Admin Groups Branding and Logos Science COVID-19 Research Programmes Scientific Groups Collaborations Tools Data Sanger Projects Publications Research Policies Sanger Seminar Series People Leadership Faculty Associate Faculty Honorary Faculty International Fellows Science Staff Non-science Staff Full A-Z Innovation Innovation at the Institute For Industry For Researchers Case Studies Our Spin-Outs Sanger Technologies News Wellcome Sanger Institute Science Our science is organised into five Scientific Programmes, each defining a major area of research with a particular biological, disease or analytic focus. In all cases, the studies provide insights into human, pathogen, cellular evolution, the phenotypic and hence biological consequences of genome variation and the processes which cause mutations. COVID-19 Research Programmes Scientific Groups Collaborations Tools Data Publications Research Policies Explore our programmes Cancer, Ageing and Somatic mutation Provides data aggregation and informatics innovation, develops high-throughput cellular models of cancer for genome-wide functional screens and drug testing, and explores the role somatic mutation plays in clonal evolution, ageing and development. Find out more Cellular Genetics Uses single-cell approaches and “cell atlas” technologies to understand human genetics at the cellular level. Combines cutting-edge techniques in wet and dry lab to further understanding of human health, development and disease. Find out more Human Genetics Drives understanding of genetic causes and biological mechanisms of disease susceptibility and progression, focuses on developmental disorders and diseases of the blood and immune system. Integrates population-scale genetics, longitudinal clinical data, and large-scale genetic perturbation studies in cellular model systems. Aims to transform the clinical utility of human genetic variation. Find out more Parasites and Microbes We are using genomics to get at important problems in infectious disease, with a strong desire to translate this into tools for disease control and elimination, but we are also at the forefront of basic research into microbial ecology, evolutionary genetics and the biology of parasitism. Find out more Tree of Life The Tree of Life Programme investigates the diversity of complex organisms (eukaryotes) found in the UK through sequencing and cellular technologies. It also compares and contrasts species’ genome sequences to unlock insights into evolution and conservation. Find out more Dan Ross COVID-19 research at the Sanger Institute We are committed to tracking, understanding and combatting COVID-19. Our staff sequence thousands of virus genomes and use the data to trace transmission, inform public health measures and monitor for new variants of the virus. We also work to understand how the virus interacts with our cells, and to develop new diagnostics COVID-19 Research Explore our science Our groups Our research is built upon our Faculty and Associate Faculty research leaders. Each develops his or her own hypothesis-driven research, seeking answers to important biomedical questions. Faculty and Associate Faculty members lead their own groups of postdoctoral fellows, PhD students and support staff. Find out more Our collaborations Our ability to conduct large-scale, high-throughput genomic studies enables our researchers to play leading roles in national and international projects: spanning cancer, infectious disease, human epidemiology and developmental disorders. Find out more Data All our software tools are made available to the research community and comply with our open-access policy, recognising that community improvement is essential to maximising efficiencies in software development. Find out more Tools As a leading genomics centre, the Sanger Institute often needs to develop software solutions to novel biological problems. Find out more Sanger Seminar Series We are hosting a series of monthly freely available and open virtual seminars, showcasing how our researchers are tackling some of the greatest challenges in human health and disease. From using genomic approaches to map all cell types in the human body, understand how cancer develops, and track the evolution and spread of global diseases, our senior scientists and faculty will present the latest developments in their field. Sanger Seminar Series AdobeStock See full index Recent publications Loading publications... Sanger Institute PhD and MPhil theses To download and read the theses of our students – from 2004 onwards – please use the link below Staff PhD and MPhil theses in pdf format Related content See all news 13 Jan 2022 Unprecedented cellular maps of tissues enabled by new tool Ability to combine cell function and spatial information key to understanding life at molecular level 22 Dec 2021 Rapid immune response in children protects them from COVID-19, genetic study finds Discovery of importance of interferon response in preventing serious infection will underpin new diagnostics and therapeutics 20 Dec 2021 Sanger researcher invited to deliver 2022 Balfour Lecture The award marks Dr Sam Behjati’s contributions to genetics research, as an outstanding young investigator Wellcome Genome Campus, Hinxton, Cambridgeshire, CB10 1SA. 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