Clinical and Histological changes after ridge preservation with two xenografts: Preliminary results from a multicentre randomized controlled clinical trial
— the UWA Profiles and Research Repository Skip to main navigation Skip to search Skip to main content the UWA Profiles and Research Repository Home Help & FAQ Home Profiles Organisations Research output Grants Datasets Prizes / Awards Engagement / Activities Press / Media Units Equipment Impacts Search by expertise, name or affiliation Clinical and Histological changes after ridge preservation with two xenografts: Preliminary results from a multicentre randomized controlled clinical trial Antonio Barone, Paolo Toti, Alessandro Quaranta, Fortunato Alfonsi, Alessandro Cucchi, Bruno Negri, Roberto Di Felice, Saverio Marchionni, Jose' Luis Calvo-Guirado, Ugo Covani, Ulf Nannmark Dental School Research output: Contribution to journal › Article › peer-review 34 Citations (Scopus) Overview Fingerprint Abstract Objectives: To evaluate and compare clinical and histological changes after ridge preservation procedures with those of spontaneous healing. Materials and Methods: Ninety patients were enrolled in the present randomized controlled clinical trial and underwent single-tooth extraction in the premolar/molar areas. Thirty sites were grafted with collagenated cortico-cancellous (coll), 30 sites with cortical (cort) porcine bone and 30 sites underwent natural healing. Primary (vertical and horizontal bone changes after 3 months) and secondary outcomes (histomorphometric after 3 months) were evaluated at implant placement. Results: The vertical bone changes at the grafted sockets were significantly (p < 0.0001) lower (0.30 mm for cort group and 0.57 mm for coll group) when compared to non-grafted sockets (2.10 mm for nat group). Moreover, the width reduction of the coll (0.93 mm) and cort (1.33 mm) groups was significantly lower (p < 0.0001) than the non-grafted group (3.60 mm). The analysis of subgroups attested that when premolar and molar sites were compared, the buccal bone loss appeared to be dependent both on tooth position and grafting material employed. Conclusion: The ridge preservation procedures had significantly better outcomes when compared to natural healing. The biomaterials did not differ for maintenance of bone width; even though, the bone height seemed to be better preserved with the cortical porcine bone. Original language English Pages (from-to) 204-214 Journal Journal of Clinical Periodontology Volume 44 Issue number 2 DOIs https://doi.org/10.1111/jcpe.12655 Publication status Published - Feb 2017 Access to Document 10.1111/jcpe.12655 Other files and links Link to publication in Scopus Fingerprint Dive into the research topics of 'Clinical and Histological changes after ridge preservation with two xenografts: Preliminary results from a multicentre randomized controlled clinical trial'. Together they form a unique fingerprint. Heterografts Medicine & Life Sciences 100% Randomized Controlled Trials Medicine & Life Sciences 75% Bone and Bones Medicine & Life Sciences 66% Cortical Bone Medicine & Life Sciences 61% Bicuspid Medicine & Life Sciences 60% Swine Medicine & Life Sciences 44% Zygoma Medicine & Life Sciences 37% Tooth Extraction Medicine & Life Sciences 33% View full fingerprint Cite this APA Author BIBTEX Harvard Standard RIS Vancouver Barone, A., Toti, P., Quaranta, A., Alfonsi, F., Cucchi, A., Negri, B., Di Felice, R., Marchionni, S., Calvo-Guirado, J. L., Covani, U., & Nannmark, U. (2017). Clinical and Histological changes after ridge preservation with two xenografts: Preliminary results from a multicentre randomized controlled clinical trial. Journal of Clinical Periodontology, 44(2), 204-214. https://doi.org/10.1111/jcpe.12655 Barone, Antonio ; Toti, Paolo ; Quaranta, Alessandro ; Alfonsi, Fortunato ; Cucchi, Alessandro ; Negri, Bruno ; Di Felice, Roberto ; Marchionni, Saverio ; Calvo-Guirado, Jose' Luis ; Covani, Ugo ; Nannmark, Ulf. / Clinical and Histological changes after ridge preservation with two xenografts : Preliminary results from a multicentre randomized controlled clinical trial. In: Journal of Clinical Periodontology. 2017 ; Vol. 44, No. 2. pp. 204-214. @article{511f20259469435c85a27401504e94aa, title = "Clinical and Histological changes after ridge preservation with two xenografts: Preliminary results from a multicentre randomized controlled clinical trial", abstract = "Objectives: To evaluate and compare clinical and histological changes after ridge preservation procedures with those of spontaneous healing. Materials and Methods: Ninety patients were enrolled in the present randomized controlled clinical trial and underwent single-tooth extraction in the premolar/molar areas. Thirty sites were grafted with collagenated cortico-cancellous (coll), 30 sites with cortical (cort) porcine bone and 30 sites underwent natural healing. Primary (vertical and horizontal bone changes after 3 months) and secondary outcomes (histomorphometric after 3 months) were evaluated at implant placement. Results: The vertical bone changes at the grafted sockets were significantly (p < 0.0001) lower (0.30 mm for cort group and 0.57 mm for coll group) when compared to non-grafted sockets (2.10 mm for nat group). Moreover, the width reduction of the coll (0.93 mm) and cort (1.33 mm) groups was significantly lower (p < 0.0001) than the non-grafted group (3.60 mm). The analysis of subgroups attested that when premolar and molar sites were compared, the buccal bone loss appeared to be dependent both on tooth position and grafting material employed. Conclusion: The ridge preservation procedures had significantly better outcomes when compared to natural healing. The biomaterials did not differ for maintenance of bone width; even though, the bone height seemed to be better preserved with the cortical porcine bone.", keywords = "Alveolar bone loss, Alveoloplasty, Bone remodelling, Tooth socket, Xenograft", author = "Antonio Barone and Paolo Toti and Alessandro Quaranta and Fortunato Alfonsi and Alessandro Cucchi and Bruno Negri and {Di Felice}, Roberto and Saverio Marchionni and Calvo-Guirado, {Jose' Luis} and Ugo Covani and Ulf Nannmark", year = "2017", month = feb, doi = "10.1111/jcpe.12655", language = "English", volume = "44", pages = "204--214", journal = "Journal of Clinical Periodontology", issn = "0303-6979", publisher = "Blackwell", number = "2", } Barone, A, Toti, P, Quaranta, A, Alfonsi, F, Cucchi, A, Negri, B, Di Felice, R, Marchionni, S, Calvo-Guirado, JL, Covani, U & Nannmark, U 2017, 'Clinical and Histological changes after ridge preservation with two xenografts: Preliminary results from a multicentre randomized controlled clinical trial', Journal of Clinical Periodontology, vol. 44, no. 2, pp. 204-214. https://doi.org/10.1111/jcpe.12655 Clinical and Histological changes after ridge preservation with two xenografts : Preliminary results from a multicentre randomized controlled clinical trial. / Barone, Antonio; Toti, Paolo; Quaranta, Alessandro; Alfonsi, Fortunato; Cucchi, Alessandro; Negri, Bruno; Di Felice, Roberto; Marchionni, Saverio; Calvo-Guirado, Jose' Luis; Covani, Ugo; Nannmark, Ulf. In: Journal of Clinical Periodontology, Vol. 44, No. 2, 02.2017, p. 204-214. Research output: Contribution to journal › Article › peer-review TY - JOUR T1 - Clinical and Histological changes after ridge preservation with two xenografts T2 - Preliminary results from a multicentre randomized controlled clinical trial AU - Barone, Antonio AU - Toti, Paolo AU - Quaranta, Alessandro AU - Alfonsi, Fortunato AU - Cucchi, Alessandro AU - Negri, Bruno AU - Di Felice, Roberto AU - Marchionni, Saverio AU - Calvo-Guirado, Jose' Luis AU - Covani, Ugo AU - Nannmark, Ulf PY - 2017/2 Y1 - 2017/2 N2 - Objectives: To evaluate and compare clinical and histological changes after ridge preservation procedures with those of spontaneous healing. Materials and Methods: Ninety patients were enrolled in the present randomized controlled clinical trial and underwent single-tooth extraction in the premolar/molar areas. Thirty sites were grafted with collagenated cortico-cancellous (coll), 30 sites with cortical (cort) porcine bone and 30 sites underwent natural healing. Primary (vertical and horizontal bone changes after 3 months) and secondary outcomes (histomorphometric after 3 months) were evaluated at implant placement. Results: The vertical bone changes at the grafted sockets were significantly (p < 0.0001) lower (0.30 mm for cort group and 0.57 mm for coll group) when compared to non-grafted sockets (2.10 mm for nat group). Moreover, the width reduction of the coll (0.93 mm) and cort (1.33 mm) groups was significantly lower (p < 0.0001) than the non-grafted group (3.60 mm). The analysis of subgroups attested that when premolar and molar sites were compared, the buccal bone loss appeared to be dependent both on tooth position and grafting material employed. Conclusion: The ridge preservation procedures had significantly better outcomes when compared to natural healing. The biomaterials did not differ for maintenance of bone width; even though, the bone height seemed to be better preserved with the cortical porcine bone. AB - Objectives: To evaluate and compare clinical and histological changes after ridge preservation procedures with those of spontaneous healing. Materials and Methods: Ninety patients were enrolled in the present randomized controlled clinical trial and underwent single-tooth extraction in the premolar/molar areas. Thirty sites were grafted with collagenated cortico-cancellous (coll), 30 sites with cortical (cort) porcine bone and 30 sites underwent natural healing. Primary (vertical and horizontal bone changes after 3 months) and secondary outcomes (histomorphometric after 3 months) were evaluated at implant placement. Results: The vertical bone changes at the grafted sockets were significantly (p < 0.0001) lower (0.30 mm for cort group and 0.57 mm for coll group) when compared to non-grafted sockets (2.10 mm for nat group). Moreover, the width reduction of the coll (0.93 mm) and cort (1.33 mm) groups was significantly lower (p < 0.0001) than the non-grafted group (3.60 mm). The analysis of subgroups attested that when premolar and molar sites were compared, the buccal bone loss appeared to be dependent both on tooth position and grafting material employed. Conclusion: The ridge preservation procedures had significantly better outcomes when compared to natural healing. The biomaterials did not differ for maintenance of bone width; even though, the bone height seemed to be better preserved with the cortical porcine bone. KW - Alveolar bone loss KW - Alveoloplasty KW - Bone remodelling KW - Tooth socket KW - Xenograft UR - http://www.scopus.com/inward/record.url?scp=85010677128&partnerID=8YFLogxK U2 - 10.1111/jcpe.12655 DO - 10.1111/jcpe.12655 M3 - Article C2 - 27883211 AN - SCOPUS:85010677128 VL - 44 SP - 204 EP - 214 JO - Journal of Clinical Periodontology JF - Journal of Clinical Periodontology SN - 0303-6979 IS - 2 ER - Barone A, Toti P, Quaranta A, Alfonsi F, Cucchi A, Negri B et al. Clinical and Histological changes after ridge preservation with two xenografts: Preliminary results from a multicentre randomized controlled clinical trial. Journal of Clinical Periodontology. 2017 Feb;44(2):204-214. https://doi.org/10.1111/jcpe.12655 Powered by Pure, Scopus & Elsevier Fingerprint Engine™ © 2021 Elsevier B.V. We use cookies to help provide and enhance our service and tailor content. By continuing you agree to the use of cookies Log in to Pure About web accessibility Contact us
