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cancer at the epigenetic and genetic levels Developing drugs to block malaria transmission Developing new computational tools for CRISPR genomics to advance cancer research Developing novel antibody-based methods for regulating apoptotic cell death Discovering novel paradigms to cure viral and bacterial infections Discovery and targeting of novel regulators of transcription Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium Do membrane forces govern assembly of the deadly apoptotic pore? Doublecortin-like kinases, drug targets in cancer and neurological disorders E3 ubiquitin ligases in neurodegeneration, autoinflammation and cancer Engineering improved CAR-T cell therapies Epigenetic biomarkers of tuberculosis infection Exploiting cell death pathways in regulatory T cells for cancer immunotherapy Finding treatments for chromatin disorders of intellectual disability Functional epigenomics in human B cells Genomic rearrangement detection with third generation sequencing technology How does DNA damage shape disease susceptibility over a lifetime? How does DNA hypermutation shape the development of solid tumours? How platelets prevent neonatal stroke Human lung protective immunity to tuberculosis Interaction with Toxoplasma parasites and the brain Interactions between tumour cells and their microenvironment in non-small cell lung cancer Investigating the role of dysregulated Tom40 in neurodegeneration Investigating the role of mutant p53 in cancer Lupus: proteasome inhibitors and inflammation Machine learning methods for somatic genome rearrangement detection Malaria: going bananas for sex Measurements of malaria parasite and erythrocyte membrane interactions using cutting-edge microscopy Measuring susceptibility of cancer cells to BH3-mimetics Minimising rheumatic adverse events of checkpoint inhibitor cancer therapy Mutational signatures of structural variation Naturally acquired immune response to malaria parasites Predicting the effect of non-coding structural variants in cancer Revealing the epigenetic origins of immune disease Reversing antimalarial resistance in human malaria parasites Structural and functional analysis of DNA repair complexes Targeting human infective coronaviruses using alpaca antibodies Towards targeting altered glial biology in high-grade brain cancers Uncovering the real impact of persistent malaria infections Understanding Plasmodium falciparum invasion of red blood cells Understanding how malaria parasites sabotage acquisition of immunity Understanding malaria infection dynamics Understanding the mechanism of type I cytokine receptor activation Unveiling the heterogeneity of small cell lung cancer Using alpaca antibodies to understand malaria invasion and transmission Using combination immunotherapy to tackle heterogeneous brain tumours Using intravital microscopy for immunotherapy against brain tumours Using nanobodies to cross the blood brain barrier for drug delivery Using structural biology to understand programmed cell death School resources Work experience Frequently asked questions Student profiles Abebe Fola Andrew Baldi Anna Gabrielyan Bridget Dorizzi Casey Ah-Cann Catia Pierotti Emma Nolan Huon Wong Jing Deng Joy Liu Kaiseal Sarson-Lawrence Komal Patel Lilly Backshell Megan Kent Naomi Jones Rebecca Delconte Roberto Bonelli Rune Larsen Runyu Mao Sarah Garner Simona Seizova Wayne Cawthorne Wil Lehmann Miles Horton Alexandra Gurzau Student achievements Student association Learning Hub News Illuminate newsletter Subscribe Events Art of Science Past exhibitions Student Open Days Discovery Tours Donate Online donation Ways to support Campaigns Discovery Fund Innovation grants Technology Circle Metcalf Scholarship Fund Support InSPIRE Community fundraising Corporate support Gift in your Will Bequestor stories Common questions Preparing your Will Walter and Eliza Hall Society Gifts in memory Donate shares Trusts and foundations Volunteer Blood Donor Registry Support outcomes Where your money goes Equipping researchers with game-changing technology Joan Marshall Breast Cancer Research Fund Run Melbourne travel scholarships Supporter stories Rotarians against breast cancer A partnership to improve treatments for cancer patients 20 years of cancer research support from the Helpman family A generous gift from a cancer survivor A gift to support excellence in Australian medical research An enduring friendship Anonymous donor helps bridge the 'valley of death' Renewed support for HIV eradication project Searching for solutions to muscular dystrophy Supporting research into better treatments for colon cancer Taking a single cell focus with the DROP-seq WEHI.TV About WEHI.TV Augmented Reality - WEHI AR Research Diseases Cancer Development and ageing Immune health and infection Search this site Research fields Bioinformatics Cancer biology Cell death Cell signalling Clinical translation Colony stimulating factors Computational biology Epigenetics Haematology Immunology Immunotherapy Infection Inflammation Personalised medicine Stem cells Systems biology Research technologies Antibody technologies Drug discovery Flow cytometry Genomics Imaging Medicinal chemistry Proteomics Structural biology Vaccine development People Looking for someone? Career Opportunities Collaboration Title: T cell receptor structure and function PhD Honours Masters Clinician-scientist training Undergraduate Student research projects School resources Frequently asked questions Student profiles Student achievements Student association Learning Hub Joy Liu PhD student View all student profiles Title: T cell receptor structure and function Homepage Homepage Header Image Multifield: Header Image: Header Image Link: Watch our latest biomedical animation Header Image: Header Image Link: The Brain Cancer Centre website Header Image: Header Image Link: WEHI - brighter together Welcome to WEHI Super Content: The Brain Cancer Centre Many minds. One focus. The Brain Cancer Centre was launched publicly on 25 October 2021. The centre was founded by Carrie’s Beanies 4 Brain Cancer and established in partnership with WEHI with support from the Victorian Government. The Brain Cancer Centre brings together the best and brightest minds with a single focus: to improve outcomes for brain cancer patients NOW and in the future. Our world-class research teams will work collaboratively to develop new treatments and trials so that patients diagnosed with brain cancer are given real hope. Learn more News New discovery to improve malaria elimination strategies WEHI researchers have made a crucial discovery about how asymptomatic malaria infections impact the body, informing potential strategies to control transmission and improve treatment outcomes. 4 May 2022 read more New research could help identify babies at risk of brain bleeds WEHI researchers have uncovered a new way to help identify babies and foetuses at high-risk of developing brain bleeds, paving the way for better early intervention. 2 May 2022 read more Burnet Institute and WEHI stand with transgender and gender diverse people Our institutes are passionate about equality and social justice and believe that LGBTQIA+ inclusion is our collective responsibility. Read our joint statement supporting transgender and gender diverse people. 29 April 2022 read more Could releasing 'handbrake' immune cells help supercharge immunity? WEHI researchers have found a way to supercharge immune cells that could enable them to clear disease and infections faster. 14 April 2022 read more Events Dr Sophia Davidson - Inflammation division Fri, 06/05/2022 - 11:00am to Fri, 06/05/2022 - 12:00pm Proteotoxic stress and Inflammation, a study on Proteasome-Associated Autoinflammatory Syndrome Davis Auditorium Details Professor Helen Abud - Monash University Mon, 09/05/2022 - 11:00am to Mon, 09/05/2022 - 12:15pm Organoids for cancer research Davis Auditorium Details Dr Emma Nolan - The University of Auckland Wed, 11/05/2022 - 9:30am to Wed, 11/05/2022 - 10:30am Radiation exposure elicits a neutrophil-driven response in healthy lung tissue that enhances metastatic colonization Online Details Dr Thomas Cotton - Ubiquitin Signalling division Wed, 11/05/2022 - 1:00pm to Wed, 11/05/2022 - 2:00pm Chain reactions: Molecular Mechanisms of RBR E3 ligases Davis Auditorium Details Empty Empty Copyright Footer Copyright Footer logo: Copyright Text: 2014 The Walter and Eliza Hall Insitute of Medical Research. 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